emodelrunner.synapses.stimuli¶

Synapse Stimuli.

Classes

`NetConSpikeDetector`([total_duration, locations])	Netcon linking output from pre-cell to post-cell's synapses.
`NrnNetStimStimulusCustom`([locations, ...])	Current stimulus based on current amplitude and time series.
`NrnVecStimStimulusCustom`([locations, start, ...])	Current stimulus based on stochastic current amplitude.

class emodelrunner.synapses.stimuli.NetConSpikeDetector(total_duration=None, locations=None)[source]¶

Bases: Stimulus

Netcon linking output from pre-cell to post-cell’s synapses.

total_duration¶

end time of connection (ms)

Type:: float

locations¶

synapse point processes locations to connect to

Type:: list

connections¶

contains simulator NetCon so that they are persistent

Type:: dict

destroy(sim=None)[source]¶

Destroy stimulus.

Parameters:: sim (bluepyopt.ephys.NrnSimulator) – neuron simulator

instantiate(sim, icell)[source]¶

Instantiate connections.

Parameters:

sim (bluepyopt.ephys.NrnSimulator) – neuron simulator
icell (neuron cell) – cell instantiation in simulator

class emodelrunner.synapses.stimuli.NrnNetStimStimulusCustom(locations=None, total_duration=None, interval=None, number=None, start=None, noise=0)[source]¶

Bases: Stimulus

Current stimulus based on current amplitude and time series.

total_duration¶

duration of run (ms)

Type:: float

locations¶

synapse point processes locations to connect to

Type:: list

interval¶

time between spikes (ms)

Type:: float

number¶

average number of spikes

Type:: int

start¶

most likely start time of first spike (ms)

Type:: float

noise¶

fractional randomness (0 deterministic, 1 negexp interval distrubtion)

Type:: float

connections¶

contains simulator NetCon and NetStim so that they are persistent

Type:: dict

destroy(sim=None)[source]¶

Destroy stimulus.

Parameters:: sim (bluepyopt.ephys.NrnSimulator) – neuron simulator

instantiate(sim=None, icell=None)[source]¶

Instantiate stimuli and connections.

Parameters:

sim (bluepyopt.ephys.NrnSimulator) – neuron simulator
icell (neuron cell) – cell instantiation in simulator

class emodelrunner.synapses.stimuli.NrnVecStimStimulusCustom(locations=None, start=None, stop=None, seed=1, vecstim_random='python', pre_spike_train=None)[source]¶

Bases: Stimulus

Current stimulus based on stochastic current amplitude.

total_duration¶

time after which no synapses are allowed to fire (ms)

Type:: float

locations¶

synapse point processes locations to connect to

Type:: list

start¶

most likely start time of first spike (ms)

Type:: float

seed¶

seed for random number generator

Type:: int

vecstim_random¶

origin of the random nmb gener. can be “python” or “neuron”

Type:: str

pre_spike_train¶

list of spike train. If None, will be generated by random numbers

Type:: list

connections¶

contains simulator NetCon and VecStim and time Vector so that they are persistent

Type:: dict

destroy(sim=None)[source]¶

Destroy stimulus.

Parameters:: sim (bluepyopt.ephys.NrnSimulator) – neuron simulator

instantiate(sim=None, icell=None)[source]¶

Instantiate stimuli and connections.

Parameters:

sim (bluepyopt.ephys.NrnSimulator) – neuron simulator
icell (neuron cell) – cell instantiation in simulator